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Study identifier: NCT05986864 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)

Condition: Neovascular Age-related Macular Degeneration  ·  Sponsor: Skyline Therapeutics (US) Inc.

PhasePhase 1/Phase 2
Planned participants68
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 1/2 clinical study to evaluate the safety, preliminary efficacy, immunogenicity, and pharmacokinetic (PK) characteristics of SKG0106 in subjects with nAMD. Based on results from the phase 1 dose escalation study, the phase 2 expansion study will be conducted.

This description comes directly from the study's public registry record.

Talk to the study team

Yongqin Wang  ·  +86 18616737445  ·  yongqin.wang@skytx.com

Always discuss trial participation with your own doctor first.

Locations (9)

Retina Vitreous Associates of Florida - Saint PetersburgSt. Petersburg, Florida, United StatesNot Yet Recruiting
Ophthalmic Consultants of BostonBoston, Massachusetts, United StatesRecruiting
Retina Consultants of TexasKaty, Texas, United StatesRecruiting
Wagner Kapoor Research InstituteNorfolk, Virginia, United StatesRecruiting
The Second Hospital Of Anhui Medical UniversityHefei, Anhui, ChinaRecruiting
Zhejiang Provincial People's HospitalHangzhou, Zhejiang, ChinaRecruiting
Eye Hospital, WMU (Zhejiang Eye Hospital)Wenzhou, Zhejiang, ChinaRecruiting
Beijing HospitalBeijing, ChinaRecruiting
Peking Union Medical College HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05986864