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Study identifier: NCT05986318 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease

Condition: Lung Cancer · Interstitial Lung Disease  ·  Sponsor: David Palma

PhasePhase 2
Planned participants98
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

In this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized using a 2 x 2 factorial design to oral N-acetylcysteine (NAC) versus placebo, and also to short course corticosteroids versus placebo.

This description comes directly from the study's public registry record.

Talk to the study team

David Palma, MD  ·  519-685-8650  ·  david.palma@lhsc.on.ca

Houda Bahig, MD  ·  514-890-8254  ·  houda.bahig.chum@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (3)

BC-Cancer Agency - VancouverVancouver, British Columbia, CanadaRecruiting
Verspeeten Family Cancer Centre, London Health Sciences CentreLondon, Ontario, CanadaRecruiting
Centre Hospitalier de l'Universite de Montreal (CHUM)Montreal, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05986318