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Study identifier: NCT05984511 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT

Condition: Hepatocellular Carcinoma · Hepatic Portal Vein Tumor Invasion · Tumor Thrombus  ·  Sponsor: Third Affiliated Hospital, Sun Yat-Sen University

PhaseNA
Planned participants234
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The present study aimed to assess the effectiveness of the combination treatment of Atezolizumab/Bevacizumab, transcatheter arterial chemoembolization (TACE) and I-125 Seeds Brachytherapy (TACE-AB-I) in patients with advanced hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT). The investigators confirmed that the combination therapy yielded better survival data than the combined administration of Atezolizumab/Bevacizumab and TACE (TACE-AB) in patients with advanced HCC and Type I/II PVTT (Based on Cheng's PVTT classification).

This description comes directly from the study's public registry record.

Talk to the study team

Mingsheng Huang, M.D. & Ph.D.  ·  +86-02085253416  ·  huangmsh@mail.sysu.edu.cn

Luwen Mu, M.D.  ·  +86-13660534361  ·  mulw@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou, Guangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05984511