Condition: Ovarian Cancer · Sponsor: Loyola University
The goal of this clinical trial is to learn about the side effects and effectiveness of this novel four-drug combination of chemotherapy (decitabine, selinexor, carboplatin and paclitaxel) on patients with relapsed ovarian, fallopian or primary peritoneal carcinoma. Recently the investigators have found that the combination of decitabine and selinexor, two Food and Drug Administration (FDA) approved chemotherapy agents, may prevent or reverse the development of drug resistance and further the remissions and duration of remissions with standard ovarian cancer chemotherapy with carboplatin and paclitaxel. As decitabine and selinexor are not FDA approved for the participant's cancer, these agents are investigational.
This description comes directly from the study's public registry record.
Patrick Stiff, MD · 708-327-3148 · pstiff@lumc.edu
Agnes Natonton, RN · 708-327-3383 · anatont@luc.edu
Always discuss trial participation with your own doctor first.
| Loyola University Medical Center | Maywood, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05983276