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Study identifier: NCT05983107 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer

Condition: HR+/HER2- Advanced Breast Cancer · Targeted Therapy  ·  Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

PhasePhase 2
Planned participants102
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

To explore the efficacy and safety of chidamide combined with endocrine in phosphoinositide-3-kinase,catalytic,alpha gene(PI3KCA) wild type hormone receptor positive(HR+)/human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer patients and to explore the efficacy and safety of Everolimus combined with endocrine therapy in patients with PI3KCA Mutant HR+/HER2- advanced breast cancer.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05983107