● Recruiting

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Condition: Psychosis Associated With Alzheimer's Disease · Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

PhasePhase 3

Planned participants1000

Who can joinAll sexes, 55 Years to 90 Years

Healthy volunteersNo

About this study

This is a Phase 3 global, multicenter, 52-week, open-label extension (OLE) rollover study for subjects completing study CN012-0026, CN012-0027 or CN012-0056. Subjects (randomized or non-randomized) who complete the 38-week CN012-0026 study, 14-week CN012-0027 study or 14-week CN012-0056 study will be eligible to enroll in CN012-0028. The primary objective of the study is to assess the long-term safety and tolerability of KarXT in subjects with psychosis associated with Alzheimer's Disease.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com · 855-907-3286 · Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (429)

Local Institution - 1029	Homewood, Alabama, United States	Withdrawn
Local Institution - 1-13H98LK9	Chandler, Arizona, United States	Withdrawn
Local Institution - 1227	Chandler, Arizona, United States	Withdrawn
Local Institution - 1116	Chandler, Arizona, United States	Withdrawn
Local Institution - 1247	Gilbert, Arizona, United States	Not Yet Recruiting
Local Institution - 1217	Phoenix, Arizona, United States	Not Yet Recruiting
Local Institution - 1044	Phoenix, Arizona, United States	Withdrawn
Local Institution - 1220	Scottsdale, Arizona, United States	Withdrawn
Advanced Research Center, Inc.	Anaheim, California, United States	Recruiting
Local Institution - 1-141NO1DG	Chino, California, United States	Not Yet Recruiting
Local Institution - 1001	Costa Mesa, California, United States	Withdrawn
Local Institution - 1151	Encino, California, United States	Withdrawn

+ 417 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05980949