← Eichor
Study identifier: NCT05977907 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

Condition: Head and Neck Squamous Cell Carcinoma  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research is being done to see if it is safe to give investigational combination of study drugs (Pembrolizumab and IO102-103) before surgery to people with surgically resectable (removable) newly diagnosed or recurrent metastatic SCCHN. This will be done by watching participants closely for possible side effects from Pembrolizumab and IO102-103. In addition, participants will be monitored for any delays to their surgery due to the study drugs.

This description comes directly from the study's public registry record.

Talk to the study team

Wojciech K Mydlarz, M.D., FACS  ·  (301) 896-3332  ·  mydlarz@jhmi.edu

Zubair Khan, M.D.  ·  410-955-3157  ·  zkhan@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (5)

Sibley Memorial HospitalWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Northwestern Memorial HospitalChicago, Illinois, United StatesNot Yet Recruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Providence Cancer InstitutePortland, Oregon, United StatesNot Yet Recruiting
Thomas Jefferson University HospitalPhiladelphia, Pennsylvania, United StatesNot Yet Recruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05977907