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Study identifier: NCT05975671 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

Condition: Sepsis · Sepsis Mrsa · Sepsis Bacteremia  ·  Sponsor: Children's Hospital of Philadelphia

PhaseNA
Planned participants52500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsis stakeholders and patients admitted to one of the participating PICUs during the study period. The intervention will at a minimum include: * Implementation of a clinical guideline indicating when vancomycin should and should not be used * Unit-level feedback on overall vancomycin use within and across centers * Clinician education.

This description comes directly from the study's public registry record.

Talk to the study team

Kathleen Chiotos, MD, MSCE  ·  215-590-5505  ·  chiotosk@chop.edu

Kai Inoki, MPH  ·  215-590-5505  ·  meyahnwid@chop.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Children's Healthcare of AtlantaAtlanta, Georgia, United StatesRecruiting
Johns Hopkins Children's CenterBaltimore, Maryland, United StatesRecruiting
St. Louis Children's HospitalSt Louis, Missouri, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05975671