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Study identifier: NCT05974722 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mesh Vs Pledgets for Repair of Paraesophageal Hernia

Condition: Paraesophageal Hernia · GERD  ·  Sponsor: David Krpata

PhaseNA
Planned participants164
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare whether the use of Ovitex mesh provides superior reduction in 2-year recurrence compared to pledgeted suture closure (no mesh) for patients undergoing paraesophageal hernia repair at the Cleveland Clinic. The main questions it aims to answer are: * Determine whether there is a difference in 2-year rates of radiographic recurrence with Ovitex versus pledgeted sutures in paraesophageal hernia repair. * Assess patient quality of life (QOL) after paraesophageal hernia repair with pledgets and mesh. A two-tailed research hypothesis will be used to determine whether there are differences between the two arms

This description comes directly from the study's public registry record.

Talk to the study team

David M Krpata, MD  ·  216 445-3441  ·  krpatad@ccf.org

William C Bennett, MD  ·  216 313-8971  ·  bennetw2@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cleveland Clinic Center for Abdominal Core HealthCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05974722