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Study identifier: NCT05974631 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluating Treatments for Suicidal Veterans With PTSD

Condition: Self-directed Violence · Post-traumatic Stress Disorder (PTSD)  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants125
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Posttraumatic Stress Disorder (PTSD) is a significant driver of suicide risk among Veterans, but there is a critical knowledge gap about how to treat PTSD among people at elevated risk for suicide. Although evidence-based treatments for PTSD reduce suicide risk, Veterans at high risk for suicidal behavior rarely receive these potentially life-saving treatments. Prior research suggests that a treatment that combines Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure protocol (DBT PE) for PTSD improves both PTSD and suicide-related outcomes. This study will evaluate whether DBT + DBT PE improves these outcomes more than Prolonged Exposure plus suicide risk management, the gold standard VA care for this population. The proposed study will also examine factors that make it easier and harder to implement these treatments in VA settings. The results will help to inform treatment guidelines for this high-priority Veteran population.

This description comes directly from the study's public registry record.

Talk to the study team

Melanie S Harned, PhD  ·  (206) 277-3650  ·  melanie.harned@va.gov

John C Fortney, PhD  ·  (206) 764-2821  ·  John.Fortney@va.gov

Always discuss trial participation with your own doctor first.

Locations (4)

Minneapolis VA Health Care System, Minneapolis, MNMinneapolis, Minnesota, United StatesRecruiting
Durham VA Medical Center, Durham, NCDurham, North Carolina, United StatesRecruiting
South Texas Health Care System, San Antonio, TXSan Antonio, Texas, United StatesRecruiting
VA Puget Sound Health Care System Seattle Division, Seattle, WASeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05974631