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Study identifier: NCT05972018 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And Catheters

Condition: Aortic Aneurysm, Abdominal · Abdominal Aortic Occlusion · Aortoiliac Occlusive Disease  ·  Sponsor: Hartford Hospital

PhasePhase 4
Planned participants14
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The goal of this pilot study is to compare single shot rectus sheath blocks of liposomal bupivacaine/bupivacaine mixture to bilateral rectus sheath catheters infused with ropivacaine (standard of care at our facility) in patients undergoing vascular surgery with an open mid-abdominal laparotomy incision. This study will assess the safety and feasibility of this approach compared to standard of care. Participants will receive either a single dose of liposomal bupivacaine/bupivacaine mixture intraoperatively at the end of surgery through bilateral rectus sheath blocks (LB/B group) or the standard of care ropivacaine intraoperatively at the end of surgery through bilateral rectus sheath blocks with the insertion of bilateral RS catheter for continuous ropivacaine infusion plus repeated daily boluses (Catheter group; standard care). They will be assessed for differences in the rate of postoperative complications, resources consumed with each intervention, as well as postoperative pain scores, opioid consumption, hospital and PACU length of stay, patient's satisfaction, and quality of recovery, and hospital length of stay.

This description comes directly from the study's public registry record.

Talk to the study team

Aseel Walker, MD  ·  (860) 972-1778  ·  aseel.walker@hhchealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

Hartford HospitalHartford, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05972018