Condition: Peritoneal Dialysis-associated Peritonitis · Sponsor: Alice Ho Miu Ling Nethersole Hospital
Biofilm formation is an important cause of catheter-related infection. In hemodialysis, use of an antibiotic-lock has been proven to be effective to manage such a complication with preservation of the central venous catheter. In peritoneal dialysis, while biofilm has been implicated in relapsing and repeat peritonitis, both of which are caused by the identical bacteria as in their preceding peritonitis episode, no adjunctive measure has been proven to be effective to eradicate the biofilm bacteria. As a result, Tenckhoff catheter removal is the only recommended option for the patients suffering from relapsing or repeat peritonitis. In this study, the investigators are going to investigate whether the use of an antibiotic-lock can be useful to eradicate the biofilm in the Tenckhoff catheter to prevent future episodes of peritonitis caused by the same organism.
This description comes directly from the study's public registry record.
Ping Kwan Chan · 26892000 · cpk618a@ha.org.hk
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| Alice Ho Miu Ling Nethersole Hospital | Tai Po, Hong Kong | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05971537