Condition: Chronic Kidney Disease · Renal Anemia · Sponsor: Astellas Pharma Global Development, Inc.
Roxadustat is a licensed medicine to treat anemia in adults with chronic kidney disease (CKD). Anemia is a low level of red blood cells. Current treatment for anemia is to have injections of medicines called erythropoietin stimulating agents (also known as ESAs) to help the bone marrow make more red blood cells. These are often given together with iron. This treatment is also available to children and teenagers with CKD. However, there are some safety concerns with ESAs. Also, as roxadustat is taken orally, this may be another option for treating anemia in children and teenagers with CKD. In this study, children and teenagers with CKD and anemia will take roxadustat for up to 52 weeks to treat their anemia. The main aim of the study is to learn how roxadustat affects anemia in children and teenagers with CKD. This is an open-label study which means the children and teenagers in the study and the clinic staff know they will be taking roxadustat. In this study, the children and teenagers with CKD who need treatment for anemia can take part. Those currently being treated with an ESA will be switched to roxadustat. Those who have not been treated with an ESA can start on roxadustat straight away. All children and teenagers in the study will take roxadustat 3 times a week for up to 52 weeks (1 year). They will start on a fixed dose of roxadustat for 4 weeks. Blood samples will be taken regularly to check hemoglobin levels. The roxadustat dose may be changed if the blood levels o…
This description comes directly from the study's public registry record.
Astellas Pharma Global Development, Inc. · 800-888-7704 · Astellas.registration@astellas.com
Always discuss trial participation with your own doctor first.
| Site BE32002 | Brussels, Belgium | Recruiting |
| Site BE32001 | Edegem, Belgium | Recruiting |
| Site BE32004 | Ghent, Belgium | Recruiting |
| Site BE32003 | Leuven, Belgium | Recruiting |
| Site BG35901 | Sofia, Bulgaria | Withdrawn |
| Site HR38501 | Zagreb, Croatia | Recruiting |
| Site HR38503 | Zagreb, Croatia | Recruiting |
| Site CZ42002 | Brno, Czechia | Recruiting |
| Site CZ42001 | Prague, Czechia | Recruiting |
| Site DK45001 | Aarhus, Denmark | Recruiting |
| Site FI35801 | Helsinki, Finland | Recruiting |
| Site DE49001 | Tübingen, Germany | Recruiting |
+ 35 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05970172