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Study identifier: NCT05968794 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Cerclage for the Reduction of Extreme Preterm Birth in Twin Pregnancies With a Short Cervix or Dilatation

Condition: Preterm Birth  ·  Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

PhaseNA
Planned participants238
Who can joinFemale, 16 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial is to assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix or cervical dilatation compared to standard treatment (no cerclage) in the prevention of extreme preterm birth \< 28 weeks of gestational age. The main question it aims to answer is: What is the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix or cervical dilatation compared to standard treatment (no cerclage) in the prevention of extreme preterm birth \< 28 weeks of gestational age? Participants will be randomly assigned to the intervention (cerclage) or comparison (no cerclage) group.

This description comes directly from the study's public registry record.

Talk to the study team

Lissa van gils, MD  ·  +31642811240  ·  TWINC@amsterdamumc.nl

Martijn A Oudijk, MD, PhD, Prof  ·  TWINC@amsterdamumc.nl

Always discuss trial participation with your own doctor first.

Locations (13)

University Medical Center AntwerpenAntwerp, BelgiumNot Yet Recruiting
University Medical Center Sint-Lucas BruggeBruges, BelgiumNot Yet Recruiting
Hospital Oost-Limburg GenkGenk, BelgiumNot Yet Recruiting
University Medical Center GentGhent, BelgiumNot Yet Recruiting
University Medical Center LeuvenLeuven, BelgiumNot Yet Recruiting
University Medical Center AmsterdamAmsterdam, NetherlandsRecruiting
University Medical Center GroningenGroningen, NetherlandsNot Yet Recruiting
University Medical Center LeidenLeiden, NetherlandsNot Yet Recruiting
University Medical Center MaastrichtMaastricht, NetherlandsNot Yet Recruiting
Radboud University Medical CenterNijmegen, NetherlandsNot Yet Recruiting
Erasmus Medical CentreRotterdam, NetherlandsNot Yet Recruiting
University Medical Center UtrechtUtrecht, NetherlandsNot Yet Recruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05968794