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Study identifier: NCT05968573 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Persuasive Health Communication Intervention for HIV/HCV

Condition: Human Immunodeficiency Virus (HIV) · Hepatitis C (HCV)  ·  Sponsor: University of South Florida

PhaseNA
Planned participants2000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

A major impediment to emergency department (ED)-based HIV/HCV screening success is that often ED patients at risk for, or later diagnosed with, HIV and HCV decline testing. In this R01 project, the research team will assess how well a promising, easy-to-use, one-time, minimal-training-needed, very brief persuasive health communication intervention (PHCI) increases acceptance of testing among adult ED patients who either currently, formerly or never injected drugs and initially declined HIV/HCV screening. The research team will conduct a randomized, controlled trial (RCT) at EDs within the Mount Sinai Health System to compare the efficacy of the PHCI when delivered by a video vs. an HIV/HCV counselor. Patients who initially declined HIV/HCV screening will be stratified by injection-drug use (IDU) history cohorts: (1) current/former PWIDs, (2) never/non-PWIDs. Within each IDU history cohort, the research team will randomly assign participants (1:1:1) to a PHCI delivered by: (1) a video with captions, (2) a video without captions, (3) an HIV/HCV counselor. This R01 project will be conducted at Mount Sinai affiliate hospitals EDs. For Aim 2, the research team will determine if screening acceptance is similar across IDU history cohorts. For Aim 3, the research team will further compare the two delivery forms of the PHCI through a health economics assessment, both independent of IDU history and within each IDU history cohort.

This description comes directly from the study's public registry record.

Talk to the study team

Roland C Merchant, MD  ·  (212) 524-9814  ·  Roland.Merchant@mountsinai.org

Always discuss trial participation with your own doctor first.

Locations (1)

Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05968573