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Study identifier: NCT05966467 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies

Condition: Neuromyelitis Optica Spectrum Disorder · NMOSD · AQP4+ NMOSD  ·  Sponsor: Alexion Pharmaceuticals, Inc.

PhaseN/A
Planned participants122
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Long-term, multicenter, multinational, observational, registry of patients with AQP4+ NMOSD that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT). The registry will also collect data on patient reported outcomes (PROs), quality of life (QoL), and targeted AQP4+ NMOSD therapies used to provide evidence on the real-world impact of ALXN-C5IT on patients with AQP4+ NMOSD.

This description comes directly from the study's public registry record.

Talk to the study team

Alexion Pharmaceuticals, Inc. (Sponsor)  ·  1-855-752-2356  ·  clinicaltrials@alexion.com

Always discuss trial participation with your own doctor first.

Locations (33)

Clinical Trial SiteWashington D.C., District of Columbia, United StatesRecruiting
Research SiteBoston, Massachusetts, United StatesRecruiting
Clinical Trial SiteChapel Hill, North Carolina, United StatesNot Yet Recruiting
Clinical Trial SiteColumbus, Ohio, United StatesRecruiting
Clinical Trial SitePlano, Texas, United StatesRecruiting
Clinical Trial SiteMilwaukee, Wisconsin, United StatesRecruiting
Clinical Trial SiteBuenos Aires, ArgentinaRecruiting
Clinical Trial SiteBuenos Aires, ArgentinaNot Yet Recruiting
Clinical Trial SiteBuenos Aires, ArgentinaRecruiting
Clinical Trial SiteBuenos Aires, ArgentinaRecruiting
Clinical Trial SiteBurnaby, British Columbia, CanadaRecruiting
Clinical Trial SiteBeijing, ChinaNot Yet Recruiting

+ 21 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05966467