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Study identifier: NCT05965076 Synced from ClinicalTrials.gov · July 28, 2026
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Analysis of the Effectiveness of the Use of Glycine Powder and Angled Implant Brush in Oral Hygiene Maintenance in Patients Reinstated With Columbus Bridge ProtocolTM

Condition: Plaque, Dental  ·  Sponsor: A.O.U. Città della Salute e della Scienza

PhaseNA
Planned participants74
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

This study aims at comparing different procedures of Professional Oral Hygiene (POH) and Domiciliary Oral Hygiene (DOH) in Columbus Bridge ProtocolTM full-arch reinstated patients by dividing a sample of at least 74 patients into 4 groups with a 1:1:1:1 ratio. The patients will randomly be assigned to a "Standard" or "Glycine Perio Flow" Professional treatment, and to a "Standard" or "Angled" Toothbrush for their Domiciliary oral hygiene. Data about bacterial plaque presence is collected both before and after unscrewing the denture, when it comes to implant abutments. Instead, Denture Plaque Index will be collected after unscrewing the denture, by means of erythrosine and analyzed using a specific software that allows to compute the percentage of plaque on the denture. Patients will be seen after 3 months in order to figure out differences between DOH groups, by measuring plaque on abutments and on the denture after unscrewing it. At the moment there are no scientific studies trying to determine which professional and domiciliary procedures might be more efficient to control bacterial plaque in Columbus Bridge ProtocolTM reinstated patients. Statistically significant lower Plaque Index (PI) and Denture Plaque Index (DPI) scores are expected in patients treated with glycine perio flow, compared to standard treated patients. However, when it comes to angled toothbrush, lower PI and DPI are expected not to be statistically significant. Expectation from this study is to get …

This description comes directly from the study's public registry record.

Talk to the study team

Armando Crupi, Dr.  ·  +39 0116331531  ·  armando.crupi@unito.it

Always discuss trial participation with your own doctor first.

Locations (1)

S.C. Riabilitazione Orale Protesi Maxillo-Facciale e Implantologia DentariaTorino, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05965076