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Study identifier: NCT05964387 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars

Condition: Molar Incisor Hypomineralization · Anesthesia, Local  ·  Sponsor: University of Michigan

PhaseNA
Planned participants50
Who can joinAll sexes, 6 Years to 11 Years
Healthy volunteersYes

About this study

The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia (MIH). The goal is to determine if pre-operative application of SDF results in improved local anesthesia and decrease in procedural pain in MIH affected teeth, thereby addressing an important challenge in routine clinical practice and contributing to the development of a treatment protocol for MIH affected molars.

This description comes directly from the study's public registry record.

Talk to the study team

James Boynton, DDS  ·  734-763-2331  ·  jboynton@umich.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of MichiganAnn Arbor, Michigan, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05964387