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Study identifier: NCT05962359 Synced from ClinicalTrials.gov · July 28, 2026
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Neural Prediction to Enhance Language

Condition: Bilateral Sensorineural Hearing Loss · Speech and Language Development Delay Due to Hearing Loss · Social Communication  ·  Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

PhaseNA
Planned participants700
Who can joinAll sexes, 0 Months to 5 Years
Healthy volunteersNo

About this study

The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing children. The research is focused upon development of neural predictive models based upon brain imaging to forecast language after cochlear implantation on the individual child level. The long-term goal is improving children's language by using predictive models to enable a custom "predict to prescribe" approach to intervene with more effective behavioral therapy for children at risk to develop poorer language. The investigators previously developed models for short term language outcome of English-learning implanted children. The aims of this study are to 1. Develop models able to predict long term outcome for English- learning and Spanish-learning children; and 2. To evaluate whether English-learning children predicted to achieve lower language based on the investigators' previously constructed models can demonstrate significant gains from Parent Implemented Communication Treatment (PICT). PICT is an intensive parent education program about strategies to improve children's communication.

This description comes directly from the study's public registry record.

Talk to the study team

Nancy M Young, MD  ·  312-227-6812  ·  nyoung@luriechildrens.org

Emily (Shimeng) Xu, PhD  ·  sxu@luriechildrens.org

Always discuss trial participation with your own doctor first.

Locations (1)

Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05962359