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Study identifier: NCT05959434 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

Condition: Posttraumatic Stress Disorder · Alcohol Use Disorder  ·  Sponsor: Texas A&M University

PhasePhase 2
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to test the efficacy of a novel integrative cognitive-behavioral intervention in patients with posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD). Specific Aim 1: Examine the efficacy of CPT-RP, as compared to RP alone, in reducing alcohol frequency (percent days drinking) and quantity (drinks per drinking day) as measured by the Timeline Follow-Back (TLFB). Specific Aim 2: Examine the efficacy of CPT-RP, as compared to RP alone, in reducing PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS-5). Specific Aim 3: Use ecological momentary assessment (EMA) to evaluate intervention effects on daily alcohol-related cognitions and behaviors through real-time associations with PTSD symptomatology and distress tolerance. Researchers will compare integrative CPT+RP with RP-alone to see if CPT+RP is more efficacious in reducing alcohol use and PTSD symptom severity.

This description comes directly from the study's public registry record.

Talk to the study team

Anka A Vujanovic, Ph.D.  ·  979-862-6538  ·  avujanovic@tamu.edu

Sudie E Back, Ph.D.  ·  backs@musc.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting
Texas A&M UniversityCollege Station, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05959434