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Study identifier: NCT05959356 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants198
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary aim of phase II CEIL study is to evaluate the efficacy of cetuximab and envafolimab plus mFOLFOXIRI versus cetuximab plus mFOLFOX6 as first line treatment of patients with initially unresectable and previously untreated RAS/BRAF wild-type, MSS, left-side metastatic colorectal cancer(mCRC), in terms of Progression-free Survival.

This description comes directly from the study's public registry record.

Talk to the study team

Yanhong Deng, Ph.D  ·  86-13925106525  ·  13925106525@163.com

Xiaoyu Xie, M.D.  ·  86-13570487315  ·  xie_xyu@163.com

Always discuss trial participation with your own doctor first.

Locations (3)

The First People's Hospital of FoshanFoshan, Guangdong, ChinaRecruiting
The Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
Affiliated Cancer Hospital of Guizhou Medical UniversityGuiyang, Guizhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05959356