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Study identifier: NCT05956847 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Role of Extracellular DNA (ecDNA) in the Occurrence and Development of Gastric

Condition: Gastric Cancer · Precancerous Lesion of Digestive Tract · Extrachromosomal DNA  ·  Sponsor: Xijing Hospital

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

ECDNA is almost non-existent in normal cells, but exists in nearly half of human cancer cells, indicating that studying such abnormal DNA is of great significance for our understanding of tumor formation and evolution. The changes in ecDNA expression in intestinal type gastric cancer may be closely related to the occurrence and development of gastric cancer. Dynamic monitoring of changes in ecDNA expression in the gastric mucosa may help predict the occurrence of gastric cancer and guide subsequent treatment. By collaborating with multiple endoscopic centers to conduct gastroscopy biopsies on patients with gastric precancerous lesions, we aim to further explore the role of ecDNA in the occurrence and development of gastric cancer through continuous follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

wei jiangpeng, PhD  ·  15389058362  ·  15389058362@163.com

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Locations (1)

Xijing Hospital of Digestive DiseasesXi'an, Shaanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05956847