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Study identifier: NCT05954741 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial

Condition: Cognitive Impairment · Dementia · Comorbidities and Coexisting Conditions  ·  Sponsor: Istituti Clinici Scientifici Maugeri SpA

PhaseNA
Planned participants75
Who can joinAll sexes, 65 Years to 80 Years
Healthy volunteersNo

About this study

Dementias secondary to cerebrovascular diseases are of significant epidemiological and clinical relevance. As a result, the management of individuals with comorbid dementia should involve early diagnosis, effective treatment, and patient-centered care planning, both in specialist and in non-specialist settings. It is well known that physical exercise can improve various aspects of health, including resistance, balance, strength, and cognitive functions such as attention and executive performance. However, the efficacy of cognitive rehabilitation is still not definitive and requires further clarification. Preliminary evidence suggests that a combination of cognitive and motor training along with novel technological approaches has the potential to maintain or improve compromised cognitive function more effectively compared to a single intervention. A multidomain intervention could enhance cognitive functioning in elderly individuals with multiple morbidities. In the present study, patients with early neurocognitive impairment based on a vascular disorder or due to multiple etiologies, as defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, will be screened in an outpatient multidisciplinary setting and subsequently undergo different models of rehabilitation training. Primary aim of this study: \- Assess the effectiveness of different rehabilitation protocols for improving cognitive functions in patients with comorbid cognitive impairment. Specifi…

This description comes directly from the study's public registry record.

Talk to the study team

Cira Fundarò, MD  ·  +39 0385247268  ·  cira.fundaro@icsmaugeri.it

Always discuss trial participation with your own doctor first.

Locations (1)

ICS Maugeri - MontescanoMontescano, Pavia, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05954741