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Study identifier: NCT05950659 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention

Condition: Diabetes · Peripheral Neuropathy · Diabetic Foot  ·  Sponsor: Johns Hopkins University

PhaseNA
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary aim of this study is to demonstrate the impact of the Orpyx® Sensory Insoles (Orpyx Medical Technologies Inc., Calgary AB, Canada) ("Orpyx" or "the Company") as an adjunct to the standard of care (SOC), as compared to SOC alone, on reducing plantar ulceration incidence in individuals who are at risk for developing diabetic foot complications. The secondary aims of this study are to evaluate participant quality of life, participant engagement, and economic impact, including cost-effectiveness and cost-utility. The study will also use the unique data set collected (plantar pressure, temperature, step count, movement and adherence feedback) to identify foot-loading histories that either lead to or prevent the development of ulceration in the diabetic foot.

This description comes directly from the study's public registry record.

Talk to the study team

Emily Bray  ·  +1 (855) 996-7799  ·  emily.bray@orpyx.com

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05950659