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Study identifier: NCT05949047 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

Condition: Caregivers · Emotions · Emotion Regulation  ·  Sponsor: Bryan Denny

PhaseNA
Planned participants270
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) not only exact a heavy toll on patients, they also impose an enormous emotional, physical, and financial burden on unpaid, often family, caregivers. The strain of providing care for a loved one diagnosed with AD, often across several years, is associated with elevated depression risk and poorer overall health. Emotion regulation skills represent an ideal target for psychological intervention to promote healthy coping in ADRD caregivers. The project seeks to use an experimental medicine approach to test the efficacy and biobehavioral mechanisms of a novel, relatively brief, targeted, scalable, smartphone-based cognitive emotion regulation intervention aimed at improving psychological outcomes (i.e., reducing perceived stress, caregiver burden, and depressive symptoms) in ADRD unpaid primary caregivers as well as examine potential benefits of the caregiver intervention on quality of life in care recipients. Cognitive reappraisal is the ability to modify the trajectory of an emotional response by thinking about and appraising emotional information in an alternative, more adaptive way. Reappraisal can be operationalized via two primary tactics: psychological distancing (i.e. appraising an emotional stimulus as an objective, impartial observer) and reinterpretation (i.e., imagining a better outcome than what initially seemed apparent). The project will investigate the efficacy and underlying biobehavioral me…

This description comes directly from the study's public registry record.

Talk to the study team

Bryan Denny, Ph.D.  ·  713-348-8257  ·  btd3@rice.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Rice UniversityHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05949047