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Study identifier: NCT05947838 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma

Condition: Appendiceal Adenocarcinoma · Colorectal  ·  Sponsor: M.D. Anderson Cancer Center

PhaseNA
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To learn if circulating tumor DNA (ctDNA) testing before cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) can show if patients have a low or high risk of the disease returning and help doctors decide if less or more intense chemotherapy is needed as treatment before surgery. ctDNA testing measures the amount of tumor DNA (genetic information) in the blood.

This description comes directly from the study's public registry record.

Talk to the study team

Michael White, MD  ·  (713) 355-0897  ·  mgwhite@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05947838