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Study identifier: NCT05947656 Synced from ClinicalTrials.gov · July 29, 2026
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Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Condition: Epilepsy, Temporal Lobe · Drug Resistant Epilepsy  ·  Sponsor: Genovate-NaviFUS (Australia) Pty Ltd.

PhaseNA
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Participants with drug-resistant epilepsy (DRE) enrolled in this study will receive focused ultrasound (FUS) treatment with the NaviFUS System, guided by the neuronavigation system to evaluate the safety and efficacy of using NaviFUS System. During the treatment, the FUS will electronically scan and target to the assigned zones on one or both of the hippocampi. The study consists of a 60-day screening period for baseline observation prior to treatment, a FUS treatment period of 2 weeks for Cohort 1 or 3 weeks for Cohort 2 with 2 FUS treatments per week using the NaviFUS System, and a safety follow-up period of 81 days.

This description comes directly from the study's public registry record.

Talk to the study team

Caitlin Roberts, Ms.  ·  +61 3 9076 2598  ·  cai.roberts@alfred.org.au

Jack Germaine, Mr.  ·  +61 3 9076 2029  ·  j.germaine@alfred.org.au

Always discuss trial participation with your own doctor first.

Locations (1)

The AlfredMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT05947656