Condition: Takotsubo Cardiomyopathy · Sponsor: University Hospital Heidelberg
The goal of this clinical trial is to investigate the impact of repetitive acute Cyclosporine A (CsA) bolus therapy in patients suffering from TTS with an elevated risk of impaired outcome. The main question it aims to answer is whether CsA reduces myocardial injury (primary outcome). Participants will receive CsA or placebo at baseline and every 12h in the first 24h after study inclusion. Researchers will compare CsA and the placebo group to see if a) myocardial injury is reduced, and b) ejection fraction is improved compared to baseline, as well as several other secondary endpoints over a one year follow-up.
This description comes directly from the study's public registry record.
Bastian Bruns, MD · +496221-56-36266 · bastian.bruns@med.uni-heidelberg.de
Always discuss trial participation with your own doctor first.
| Kerckhoff Heart Center, Bad Nauheim / Gießen University | Bad Nauheim, Germany | Recruiting |
| Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin | Berlin, Germany | Recruiting |
| Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum | Berlin, Germany | Recruiting |
| Heart Centre - University Hospital Bonn | Bonn, Germany | Recruiting |
| Department of Cardiology, University Hospital Köln | Cologne, Germany | Recruiting |
| Department of Cardiology, University Hospital Dresden | Dresden, Germany | Recruiting |
| Cardiovascular Centre - University Hospital Düsseldorf | Düsseldorf, Germany | Recruiting |
| Department of Cardiology - University Hospital Essen | Essen, Germany | Recruiting |
| Department of Cardiology, University Hospital Frankfurt | Frankfurt, Germany | Recruiting |
| University Medical Center Göttingen | Göttingen, Germany | Recruiting |
| Department of Cardiology, University Hospital Halle | Halle, Germany | Recruiting |
| University Medical Center Hamburg-Eppendorf | Hamburg, Germany | Recruiting |
+ 12 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05946772