Condition: Osteoarthritis, Knee · Sponsor: Wake Forest University
The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or infrequent knee pain. The primary aim is to compare the effects of a dietary weight loss, exercise, and weight-loss maintenance to an attention control group in preventing the development of structural Magnetic Resonance Imaging (MRI) knee OA. Secondary aims will determine the intervention effects on pain, mobility, health-related quality of life, knee joint compressive forces, inflammatory measures, weight loss, exercise self-efficacy, and cost-effectiveness of this intervention.
This description comes directly from the study's public registry record.
Jovita Newman · 336-758-3969 · jollajk@wfu.edu
Always discuss trial participation with your own doctor first.
| Brigham and Women's Hospital | Boston, Massachusetts, United States | Recruiting |
| University of North Carolina at Chapel Hill | Chapel Hill, North Carolina, United States | Active Not Recruiting |
| Wake Forest University | Winston-Salem, North Carolina, United States | Recruiting |
| University of Sydney | Sydney, Australia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05946044