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Study identifier: NCT05943665 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MDMA for AUD/PTSD Comorbidity

Condition: Alcohol Use Disorder · Post Traumatic Stress Disorder  ·  Sponsor: Carolina L Haass-Koffler

PhasePhase 2
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study investigators are conducting the first open label pilot trial of MDMA-assisted therapy (MDMA-AT) with a comorbid sample of military veterans with a comorbid diagnosis of Alcohol Use Disorder (AUD) and Post-Traumatic Stress Disorder (PTSD). This novel experimental treatment package consists of two once-monthly Experimental Sessions of therapy combined with a divided-dose of MDMA HCl, along with non-drug preparatory and integrative therapy. The Primary Outcome measure, the Timeline Follow-back (TLFB), will evaluate changes in alcohol use over time. Changes in PTSD symptoms will also be evaluated.

This description comes directly from the study's public registry record.

Talk to the study team

Christy Capone, PhD  ·  401-273-7100  ·  christy_capone@brown.edu

Erica Eaton, PhD  ·  401-273-7100  ·  erica_eaton@brown.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Brown UniversityProvidence, Rhode Island, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05943665