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Study identifier: NCT05942430 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Autologous Costal Osteochondral Transplantation for Talar Osteochondral Lesions

Condition: Articular Cartilage Defect  ·  Sponsor: The Third Affiliated Hospital of Southern Medical University

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the effectiveness and safety of autologous costal osteochondral transplantation in the treatment of Hepple Stage V talar osteochondral lesions, compared with autologous osteoperiosteal transplantation. The main question it aims to answer is: • Whether autologous costal osteochondral transplantation can achieve better clinical outcomes and cartilage repair quality with lower donor site morbidity than autologous osteoperiosteal transplantation in the treatment of Hepple Stage V talar osteochondral lesions. Participants will be randomly assigned to the intervention group (undergoing autologous costal osteochondral transplantation) or the control group (undergoing autologous osteoperiosteal transplantation). Both groups of participants will receive the same postoperative rehabilitation process and follow-up evaluation.

This description comes directly from the study's public registry record.

Talk to the study team

Hao Guo, MD  ·  +8617612003968  ·  416363977@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Third Affiliated Hospital of Southern Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05942430