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Study identifier: NCT05939414 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Condition: Oligometastatic Prostate Cancer (OMPC)  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants450
Who can joinMale, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after definitive therapy to their primary tumor. The data generated from this study will provide evidence for the treatment of AAA617 in early-stage prostate cancer patients to control recurrent tumor from progressing to fatal metastatic disease while preserving quality of life by delaying treatment with androgen deprivation therapy (ADT).

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111  ·  novartis.email@novartis.com

Always discuss trial participation with your own doctor first.

Locations (147)

Highlands Oncology GroupFayetteville, Arkansas, United StatesRecruiting
VA Greater LA Healthcare SystemLos Angeles, California, United StatesRecruiting
VA Palo Alto Health Care SystemPalo Alto, California, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
UCSFSan Francisco, California, United StatesRecruiting
Rocky Mountain Cancer CentersDenver, Colorado, United StatesRecruiting
Cancer Specialists of North FloridaJacksonville, Florida, United StatesRecruiting
Woodlands Medical SpecialistsPensacola, Florida, United StatesRecruiting
Piedmont HealthcareAtlanta, Georgia, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
The Cancer Institute of Alexian BrothersElk Grove, Illinois, United StatesRecruiting
Unity Point ClinicDes Moines, Iowa, United StatesRecruiting

+ 135 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05939414