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Study identifier: NCT05938192 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Multimodality Treatments of HPV-related Lesions of the Female Genital Tract

Condition: HPV · Cervical Cancer · Cervix Lesion  ·  Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhaseN/A
Planned participants200
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cervical cancer is one of the most preventable types of cancer, as it develops over an extended period, and its causative agent is well-known. Persistent infection with human papillomavirus (HPV) is the primary factor causing cervical cancer. Generally, persistent HPV infection leads to cervical dysplasia (also known as cervical intraepithelial neoplasia), which can potentially progress to cancer. Although the majority of women with HPV infection will never develop lesions, a relatively high number of women remain at risk of developing cervical dysplasia. Women with cervical dysplasia who receive appropriate follow-up and treatment are at low risk of developing cervical cancer. However, recurrent cervical dysplasia is a well-known risk factor for cervical cancer. Furthermore, recurrent cervical dysplasia can contribute to morbidity, as additional surgical treatments are associated with fertility and obstetric complications in women who wish to preserve their childbearing potential. Against this background, identifying the best treatment modality for patients with cervical dysplasia is of paramount importance. The management of residual or recurrent dysplasia after primary treatment is often challenging. Moreover, it is important to classify patients based on their risk of having persistent or recurrent dysplasia following initial treatment. Assessing these risk categories is useful in tailoring appropriate surveillance and determining the need for adjunctive treatments. Our …

This description comes directly from the study's public registry record.

Talk to the study team

Giorgio Bogani, md  ·  917-275-6975  ·  giorgiobogani@yahoo.it

Giorgio Bogani  ·  917-275-6975  ·  giorgiobogani@yahoo.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Istituto Nazionale dei Tumori di MilanoMilan, Lombardy, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05938192