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Study identifier: NCT05936619 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System

Condition: Paralysis; Quadriplegic  ·  Sponsor: Nader Pouratian

PhaseNA
Planned participants2
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This research study is being done to develop a novel brain-computer interface (BCI) technology that can enable severely paralyzed individuals to interact with the world through direct brain-control of a computer. This technology is named MindEx (for Mind Extender). It utilizes four implanted "chips" in the human brain from which investigators can record brain activity during subjects' thoughts and decode meaningful information from this activity to be used as control signals for a computer, a laptop, or a tablet. The use of four brain regions is a significant differentiating feature and scientific innovation of this study over much prior work in this space, that typically derived control signals from one, or sometimes two brain regions. The brain regions to be used here can allow the decode of multiple variables simultaneously, including not just moment-to-moment position, but also high-level goals, intentions, decisions, scene comprehension, and error-related signals involved in natural human behavior. The research is being done through a prospective, longitudinal, single-arm early feasibility study to examine the safety and effectiveness of using MindEx to provide the user an intuitive, efficient, and accurate ability to control multiple applications on a computer interface such as a word processor, a paint application, or to play simple video games. Such versatility could greatly improve the autonomy and quality of life of severely paralyzed individuals. Two subjects will …

This description comes directly from the study's public registry record.

Talk to the study team

Aniah Daniels, BS  ·  214-645-8003  ·  aniah.daniels@utsouthwestern.edu

Nader Pouratian, MD, PhD  ·  214-645-5465  ·  nader.pouratian@utsouthwestern.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UT Southwestern Medical CenterDallas, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05936619