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Study identifier: NCT05936359 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

Condition: Myeloproliferative Neoplasms  ·  Sponsor: Incyte Corporation

PhasePhase 1
Planned participants225
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being conducted to evaluate the safety, tolerability, and dose-limiting toxicity (DLT) and determine the maximum tolerated dose (MTD) and/or recommended dose(s) for expansion (RDE) of INCA033989 administered as a monotherapy or in combination with ruxolitinib in participants with myeloproliferative neoplasms.

This description comes directly from the study's public registry record.

Talk to the study team

Incyte Corporation Call Center (US)  ·  1.855.463.3463  ·  medinfo@incyte.com

Incyte Corporation Call Center (ex-US)  ·  +800 00027423  ·  eumedinfo@incyte.com

Always discuss trial participation with your own doctor first.

Locations (29)

Royal Brisbane and Women'S HospitalHerston, Queensland, AustraliaRecruiting
Royal Adelaide HospitalAdelaide, South Australia, AustraliaRecruiting
Peter Maccallum Cancer CentreMelbourne, Victoria, AustraliaRecruiting
The Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Princess Margaret Cancer CenterToronto, Ontario, CanadaRecruiting
Hopital Maisonneuve-Rosemont, Montreal, QcMontreal, Quebec, CanadaRecruiting
Odense University HospitalOdense C, DenmarkWithdrawn
Sjaellands UniversitetshospitalRoskilde, DenmarkRecruiting
Vejle HospitalVejle, DenmarkRecruiting
Institut BergonieBordeaux, FranceRecruiting
Chu NimesNîmes, FranceRecruiting
Hospital Saint LouisParis, FranceRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05936359