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Study identifier: NCT05935748 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Condition: ccRCC · Clear Cell Renal Cell Carcinoma · Kidney Cancer  ·  Sponsor: NiKang Therapeutics, Inc.

PhasePhase 2
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of the Lead-in phase of the study is to evaluate the safety, efficacy, pharmacokinetics (PK) and determine recommended dose for expansion (RDE) of NKT2152 in combination with palbociclib (Doublet) and with palbociclib and sasanlimab (Triplet) in subjects with advanced or metastatic clear cell renal cell carcinoma (ccRCC) who received prior therapy. The goal of the Expansion phase of the study is to evaluate the safety, efficacy, PK at the selected RDE and identify the RP2D for NKT2152 in combination with palbociclib (Doublet) and with palbociclib and sasanlimab (Triplet) in subjects with advanced or metastatic clear cell renal cell carcinoma (ccRCC) who received prior therapy.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (8)

University of California San DiegoLa Jolla, California, United States
Northwestern University - Feinberg School of MedicineChicago, Illinois, United States
Dana-Farber Cancer InstituteBoston, Massachusetts, United States
University of Michigan-Rogel Cancer CenterAnn Arbor, Michigan, United States
Nebraska Cancer SpecialistsOmaha, Nebraska, United States
Memorial Sloan Kettering Cancer CenterNew York, New York, United States
UT Southwestern Medical CenterDallas, Texas, United States
University of Virginia Health SystemCharlottesville, Virginia, United States

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Source record: clinicaltrials.gov/study/NCT05935748