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Study identifier: NCT05935215 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Condition: Atypical Hemolytic Uremic Syndrome  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants50
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

The purpose of this Phase 3 study is to evaluate the efficacy and safety of iptacopan upon switching from anti-C5 antibody to iptacopan treatment in study participants with aHUS.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (31)

Novartis Investigative SiteNanjing, Jiangsu, ChinaWithdrawn
Novartis Investigative SiteBeijing, ChinaActive Not Recruiting
Novartis Investigative SiteBeijing, ChinaActive Not Recruiting
Novartis Investigative SiteShanghai, ChinaWithdrawn
Novartis Investigative SiteBordeaux, FranceRecruiting
Novartis Investigative SiteParis, FranceRecruiting
Novartis Investigative SiteParis, FranceRecruiting
Novartis Investigative SiteRouen, FranceRecruiting
Novartis Investigative SiteToulouse, FranceRecruiting
Novartis Investigative SiteTours, FranceRecruiting
Novartis Investigative SiteEssen, GermanyRecruiting
Novartis Investigative SiteKiel, GermanyRecruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05935215