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Study identifier: NCT05931289 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Suicide Risk Interventions

Condition: Suicide  ·  Sponsor: VA Office of Research and Development

PhasePhase 2
Planned participants136
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 female and male Veterans who have been hospitalized for suicide risk and randomly assign them to receive one of two psychotherapy treatments for suicide risk after they leave the hospital. The goals of this study are to examine if a) a longer psychotherapy causes greater improvements in coping skills and reductions in negative suicidal thinking, b) a longer psychotherapy is more effective in reducing suicide risk, and c) if Veterans with a history of multiple suicide attempts are more likely to benefit from the longer psychotherapy. Additionally, this study will use magnetic resonance imaging (MRI) neuroimaging scans of Veterans shortly after they leave the hospital and again 4- and 12-months later. This study will explore a) if brain markers can predict suicide attempts, b) if brain markers change over time as suicide risk changes, and c) if brain markers change differently for the two types of psychotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Michael S Esterman, PhD  ·  (857) 364-4362  ·  Michael.Esterman@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MABoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05931289