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Study identifier: NCT05926102 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)

Condition: Prostate Cancer  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants5000
Who can joinMale, 55 Years to 69 Years
Healthy volunteersYes

About this study

Prostate cancer is the most common non-skin cancer among Veterans and the second leading cause of male cancer death. Current methods of screening men for prostate cancer are inaccurate and cannot identify which men do not have prostate cancer or have low-grade cases that will not cause harm and which men have significant prostate cancer needing treatment. False-positive screening tests can result in unnecessary prostate biopsies for men who do not need them. However, new genetic testing might help identify which men are at highest risk for prostate cancer. This study will examine whether a genetic test helps identify men at risk for significant prostate cancer while helping men who are at low risk for prostate cancer avoid unnecessary biopsies. If this genetic test proves beneficial, it will improve the way that healthcare providers screen male Veterans for prostate cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Charles A Brunette, PhD  ·  (857) 364-6324  ·  charles.brunette@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MABoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05926102