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Study identifier: NCT05924074 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS)

Condition: Myelodysplastic Syndromes · Ferroptosis  ·  Sponsor: University Hospital, Bordeaux

PhaseNA
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Myelodysplastic syndromes (MDS) are clonal diseases of hematopoietic stem cells (HSC) characterized by dysplastic and inefficient hematopoiesis related to excessive progenitor cell death. Ferroptosis is a recently described cell death mechanism and we think that it could be a major player in the pathophysiology of MDS, involved in the cell death that characterizes these diseases and contributing to cytopenias. The study aims to demonstrate that there is a significant activation of this phenomenon in MDS patients compared to a population of subjects without MDS.

This description comes directly from the study's public registry record.

Talk to the study team

Victor-Emmanuel BRETT  ·  0556774357  ·  victor.brett@chu-bordeaux.fr

Charles DUSSIAU  ·  charles.dussiau@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (3)

CHU de Bordeaux, Laboratoire d'HématologiePessac, FranceNot Yet Recruiting
CHU de Bordeaux, Service de Médecine InternePessac, FranceNot Yet Recruiting
CHU de Bordeaux, Service Hématologie Clinique et Thérapie CellulairePessac, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05924074