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Study identifier: NCT05920382 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.

Condition: Chronic Post-surgical Pain · Chronic Post Operative Pain · Chronic Knee Pain  ·  Sponsor: Consorci Sanitari de l'Alt Penedès i Garraf

PhaseNA
Planned participants86
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Knee osteoarthritis pain is one of the conditions commonly seen in general and specialized medicine. Knee arthroplasty is one of the most successful orthopedic surgeries for the treatment of this disease, significantly improving pain, disability, and the overall quality of life for patients who undergo it. However, there is a subgroup of individuals in whom the pain persists or even worsens. Radiofrequency has been introduced over 10 years ago as a neuroablative technique targeting the genicular nerves, which innervate the sensory terminals of the knee joint, for the treatment of chronic pain in that region before or after arthroplasty. However, the results have not been entirely consistent. Recent anatomical studies have demonstrated the presence of other sensory terminal branches of the femoral nerve, such as the infrapatellar branch of the saphenous nerve, medial vastus nerve, intermediate vastus nerve, and lateral vastus nerve, which could be useful targets for the treatment of post-knee arthroplasty pain. To date, no studies have been conducted to address post-knee arthroplasty pain through the application of thermal radiofrequency on the sensory branches of the knee from the femoral nerve (infrapatellar branch of the saphenous nerve, medial vastus nerve, intermediate vastus nerve, lateral vastus nerve). Therefore, The investigators aim to conduct a randomized double-blind clinical trial where The investigators will apply thermal radiofrequency on the sensory terminal br…

This description comes directly from the study's public registry record.

Talk to the study team

ITALO G PISANI, MD  ·  +34649034623  ·  italopisani1976@gmail.com

ALEJANDRO RODRIGUEZ, PHD  ·  +34607214125  ·  ARODRIGUEZ@CSAPG.CAT

Always discuss trial participation with your own doctor first.

Locations (1)

Consorci Sanitari Alt'Pènedes i GarrafBarcelona, Catalonia, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT05920382