Condition: Severe Chest Trauma · Sponsor: University Hospital, Grenoble
Blunt chest trauma is commonly associated with rib fractures and early pain management is a key goal after chest trauma. In spontaneous breathing patients, pain limits coughing efficiency and secretion clearance, thereby potentially leading to progressive atelectasis, loss of functional residual capacity (FRC) and, ultimately, respiratory distress. In patients under mechanical ventilation, pain interacts with the weaning of mechanical ventilation inducing an increase of the duration of invasive ventilation. According to recent French guidelines for chest trauma management, immediate analgesia is initially performed by intravenous multimodal analgesia followed by a thoracic epidural analgesia or a paravertebral block if the pain is not controlled within the first 12 hours. However, these blocks necessitate an experienced anaesthesiologist, are at risk of severe complications and are contraindicated in case of post-traumatic coagulopathy. All these considerations limit their indication in the trauma bay. The erector spinae plane (ESP) block is an easy to perform, ultrasound guided, regional anaesthesia for pain management after thoracic surgery. This block can be made continuously with a dedicated catheter for a continuous infusion of local anaesthetic drug with boli. The ESP block is performed by depositing the local anaesthetic in the fascial plane, deeper than the erector spinae muscle at the tip of the transverse process of the vertebra. This block is less invasive with few…
This description comes directly from the study's public registry record.
BOUZAT Pierre, MD, PhD · 0476766879 · pbouzat@chu-grenoble.fr
ADOLLE Anaïs · 0476766879 · aadolle@chu-grenoble.fr
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| Hôpital d'instruction des armées Percy | Clamart, France | Recruiting |
| CHU Clermont-Ferrand | Clermont-Ferrand, France | Recruiting |
| Hopital Beaujon - AP-HP | Clichy, France | Recruiting |
| CH Annecy Genevois | Épagny, France | Recruiting |
| CHU Grenoble Alpes | Grenoble, France | Recruiting |
| CHU de Lille | Lille, France | Recruiting |
| Hôpital Pitie Salpetriere - AP-HP | Paris, France | Recruiting |
| Hôpital Européen Georges Pompidou - AH-HP | Paris, France | Recruiting |
| Hôpital Lyon Sud | Pierre-Bénite, France | Recruiting |
| Hôpital d'Instruction des Armées Sainte Anne | Toulon, France | Recruiting |
| Chu Toulouse - Hopital Rangueil | Toulouse, France | Recruiting |
+ 2 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05920109