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Study identifier: NCT05919329 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

Condition: Castration Resistant Prostate Cancer · Castration Sensitive Prostate Cancer · Prostate Adenocarcinoma  ·  Sponsor: OHSU Knight Cancer Institute

PhasePhase 4
Planned participants80
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial investigates the change in prostate-specific membrane antigen (PSMA) expression in response to hormonal therapy in both, Castration Sensitive Prostate Cancer (CSPC) and Castration Resistant Prostate Cancer (CRPC), and whether this change in PSMA expression changes tumor staging after therapy initiation. Understanding these effects can help define the best timing to perform the PSMA positron emission tomography (PET) relative to the start of therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Lauren Drake  ·  503-494-4960  ·  RADResearch@ohsu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

OHSU Knight Cancer InstitutePortland, Oregon, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05919329