Condition: Esophageal Squamous Cell Carcinoma · Sponsor: Renmin Hospital of Wuhan University
This study is a multicentre, randomised, parallel-controlled, open-label, 3 phase clinical trial. The subjects were untreated, unresectable locally advanced, recurrent or metastatic esophageal squamous cell carcinoma with low PD-L1 expression. Patients were randomly assigned to receive chemoradiation or chemotherapy in combination with Tislelizumab at a ratio of 1: 1. The primary endpoint was progression-free survival (PFS) in the intention-to-treat population. We hypothesized that in advanced esophageal squamous cell carcinoma patients with low PD-L1 expression, chemoradiation versus chemotherapy in combination with Tislelizumab will significantly improve PFS.
This description comes directly from the study's public registry record.
Yongshun Chen, MD · +86 15327122084 · yongshun2007@163.com
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| Renmin hosptial of Wuhan University | Wuhan, Hubei, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05919030