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Study identifier: NCT05918575 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

Condition: Obesity, Morbid · Extubation Failure  ·  Sponsor: Rush University Medical Center

PhaseNA
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hospital stays, and death. The purpose of this study is to assess if prophylactic use of noninvasive breathing support after removing the breathing tube lowers the chance of needing the breathing tube again.

This description comes directly from the study's public registry record.

Talk to the study team

Ramandeep Kaur, PhD  ·  3129478898  ·  ramandeep_kaur@rush.edu

Babak Mokhlesi, MD  ·  (312) 563-0843  ·  babak_mokhlesi@rush.edu

Always discuss trial participation with your own doctor first.

Locations (5)

Rush University Medical CenterChicago, Illinois, United StatesRecruiting
Central DuPage HospitalWinfield, Illinois, United StatesNot Yet Recruiting
McGovern Medical School, The University of Texas Health Science CenterHouston, Texas, United StatesRecruiting
Medical College of WisconsinMilwaukee, Wisconsin, United StatesRecruiting
Hospital Civil Fray Antonio AlcaldeGuadalajara, Jalisco, MexicoRecruiting

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Source record: clinicaltrials.gov/study/NCT05918575