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Study identifier: NCT05918302 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.

Condition: Neuroendocrine Tumors · Lung Neuroendocrine Neoplasm · Thymus Neoplasms  ·  Sponsor: Grupo Espanol de Tumores Neuroendocrinos

PhasePhase 3
Planned participants170
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

LEVEL trial aims to demonstrate the higher efficacy of 177Lu-edotreotide over everolimus in patients with well to moderately differentiated neuroendocrine tumors of the lung and thymus who require systemic therapy. It is hypothesized that 177Lu-edotreotide may significantly increase the progression-free survival (PFS) compared to everolimus in lung and thymic carcinoids.

This description comes directly from the study's public registry record.

Talk to the study team

Federico Nepote  ·  +34934344412  ·  investigacion@mfar.net

Always discuss trial participation with your own doctor first.

Locations (27)

Antwerp University Hospital (UZA)Edegem, Edegem, BelgiumRecruiting
UCL Saint-LucBrussels, BelgiumRecruiting
CHU LiègeLiège, BelgiumRecruiting
Hospital Center University Dijon Bourgogne (CHU Bourgogne)Dijon, Dijon, FranceRecruiting
Centre Hospitalier Universitaire (CHU) BordeuxBourdeaux, FranceRecruiting
Lille University HospitalLille, FranceRecruiting
Hôpital Edouard Herriot, LyonLyon, FranceRecruiting
Department of Nuclear Medicine, La Timone University Hospital, CERIMED, Aix-Marseille University, FranceMarseille, FranceRecruiting
Department of Digestive Oncology, CHU Saint Eloi, Montpellier, France/ ICM Cancer Institute at MontpellierMontpellier, FranceRecruiting
Centre Hospitalier Universitaire de NantesNantes, FranceRecruiting
I. Gustave Roussy, ParisParis, FranceRecruiting
Azienda USL IRCCS Di Reggio EmiliaReggio Emilia, Reggio Emilia, ItalyRecruiting

+ 15 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05918302