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Study identifier: NCT05918211 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

Condition: Single Ventricle Heart Disease  ·  Sponsor: Mezzion Pharma Co. Ltd

PhasePhase 3
Planned participants436
Who can joinAll sexes, 12 Years to 18 Years
Healthy volunteersNo

About this study

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent who have had the Fontan procedure.

This description comes directly from the study's public registry record.

Talk to the study team

WG Kim  ·  443.699.6746  ·  wgkim@mezzion.com

Always discuss trial participation with your own doctor first.

Locations (40)

Phoenix Children's HospitalPhoenix, Arizona, United StatesRecruiting
Arkansas Children'sLittle Rock, Arkansas, United StatesRecruiting
Children's Hospital of Los AngelesLos Angeles, California, United StatesRecruiting
Rady Children's HospitalSan Diego, California, United StatesRecruiting
UCSF Benioff Children's HospitalSan Francisco, California, United StatesRecruiting
Children's Hospital of ColoradoDenver, Colorado, United StatesRecruiting
Yale School of MedicineNew Haven, Connecticut, United StatesRecruiting
Nemours Children's HospitalWilmington, Delaware, United StatesRecruiting
Childrens National Medical CenterWashington D.C., District of Columbia, United StatesRecruiting
UF Health Shands HospitalGainesville, Florida, United StatesRecruiting
Joe DiMaggio Children's HospitalHollywood, Florida, United StatesRecruiting
Johns Hopkins All Children's HospitalSt. Petersburg, Florida, United StatesRecruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05918211