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Study identifier: NCT05914805 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss (SCALP2)

Condition: Alopecia, Androgenetic  ·  Sponsor: Cassiopea SpA

PhasePhase 3
Planned participants762
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of the study is to see if Clascoterone can help people with male pattern hair loss to recovery and see if the treatment is effective and safe and how well the drug is tolerated by subjects. Within this study, the Clascoterone solution will be compared to a placebo. The study has 2 parts: Part 1 will see if Clascoterone solution is effective and safe compared to a placebo when applied twice daily for up to 6 months. Part 2 will see the long-term safety and efficacy of the Clascoterone solution compared to placebo for additional 6 months in subjects defined as ''responders'' in Part 1. A responder is defined as someone who have responded to the study drug, based on research data. Part 1 of the study is double-blind, meaning that neither the subject nor the study doctor knows which treatment subject is receiving. Part 2 of the study is single-blind and only the study doctor doing the study knows which treatment subject is receiving. Part 1 of the study will start with baseline visit during which subjects will be randomly assigned (by chance) in ratio 2:1 to apply either Clascoterone or placebo solution to their balding areas of the scalp. Subjects will have 5 clinic visits and 2 follow-up phone calls during 6 months of Part 1 duration. Subjects identified as Part 1 responders at Month 6 visit will be again randomly assigned in ratio 2:1 to receive either study drug or placebo. Part 2 of the study will consist of 2 additional clinic visits and treatment will la…

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (27)

Investigate MDScottsdale, Arizona, United States
Physician's Institute of Cosmetic and Reconstructive SurgeryHollywood, Florida, United States
DelRicht ResearchAtlanta, Georgia, United States
Revival Research InstituteTroy, Michigan, United States
Grekin Skin InstituteWarren, Michigan, United States
DelRicht ResearchWildwood, Missouri, United States
Piedmont Plastic Surgery and DermatologyHuntersville, North Carolina, United States
Advanced Dermatology & Cosmetic SurgerySpartanburg, South Carolina, United States
DelRicht ResearchThompson's Station, Tennessee, United States
Austin Institute for Clinical ResearchPflugerville, Texas, United States
Acclaim Dermatology LLCSugar Land, Texas, United States
Premier Clinical ResearchSpokane, Washington, United States

+ 15 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05914805