Condition: HER2 Low Breast Carcinoma · Sponsor: Henan Cancer Hospital
HR-positive breast cancers accounts for about 50% to 60% of all breast cancer patients. Neoadjuvant Chemotherapy is the core treatment mode for this type of breast cancer, and endocrine therapy can be used in some low-risk patients. However, the pathological complete response (pCR) rate obtained is low. HER2 is an important prognostic indicator and therapeutic target for breast cancer. Nearly 60% of HR-positive breast cancers have low expression of HER2, and antibody-drug conjugates (ADC) targeting HER2 may achieve better efficacy in this subtype.
This description comes directly from the study's public registry record.
Zhenzhen Liu, Professor · +86-13603862755 · liuzhenzhen73@126.com
Jiujun Zhu, PhD · +86-13676962766 · bigapple0601@126.com
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| Henan Cancer Hospital | Zhengzhou, Henan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05911958