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Study identifier: NCT05910944 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

European Study of Prodromal iNPH

Condition: Normal Pressure Hydrocephalus · Hydrocephalus  ·  Sponsor: Johan Virhammar

PhaseN/A
Planned participants140
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

To investigate if progression from prodromal into symptomatic NPH can be predicted from advanced neuroimaging, biomarkers in cerebrospinal fluid (CSF) and plasma and investigate the unknown mechanisms causing deterioration by investigating longitudinal changes in the above-mentioned variables. Three different cohorts with both asymptomatic and symptomatic patients as well as healthy controls will be investigated over time, both without intervention and before and after shunt surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Johan Virhammar, MD, PhD  ·  +46186110000  ·  johan.virhammar@neuro.uu.se

Always discuss trial participation with your own doctor first.

Locations (7)

Kuopio University HospitalKuopio, FinlandNot Yet Recruiting
Bellaria HospitalBologna, ItalyRecruiting
Sahlgrenska University HospitalGothenburg, SwedenNot Yet Recruiting
Linköping University HospitalLinköping, SwedenNot Yet Recruiting
Karolinska University HospitalStockholm, SwedenNot Yet Recruiting
Umeå University HospitalUmeå, SwedenNot Yet Recruiting
Uppsala University HospitalUppsala, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT05910944